References:

  1. Global Infectious Diseases and Epidemiology Online Network: Infectious Diseases of the Philippines, 2013 eBook Edition, ISBN 978-1-61755-582-4, by Stephen Berger. Accessed here.

AgentPARASITE - Nematoda. Phasmidea: Enterobius vermicularis
ReservoirHuman
VectorNone
VehicleFecal-oral
Air
Clothing
Sexual contact (rare)
Incubation Period14 to 42 days
Diagnostic TestsApply scotch tape to anal verge in a.m. and paste onto glass slide for microscopy.
Typical Adult TherapyAlbendazole 400 mg PO as single dose - repeat in 2w. OR Mebendazole 100 mg PO as single dose -
repeat in 2w. OR Pyrantel pamoate 11 mg/kg (max 1g) PO as single dose
Typical Pediatric TherapyMebendazole 100 mg PO as single dose (>age 2) - repeat in 2w. OR Pyrantel pamoate 11 mg/kg
(max 1g) PO X 1
Clinical HintsNocturnal anal pruritus; occasionally vaginitis or abdominal pain; eosinophilia is rarely, if ever,
encountered.
SynonymsEnterobio, Enterobius vermicularis, Oxyuriasis, Oxyuris, Pinwom, Seatworm.

The typical manifestation of enterobiasis is nocturnal pruritus ani related to hypersensitivity to worm antigens.

  • Local dermal “tingling” is also encountered.
  • Migration of adult females to the vulva may result in vaginal pain and vulvovaginits, or predispose to urinary tract infection.
  • Eosinophilia is occasionally present.

Complications are rare, and include salpingitis, cystitis, peritonitis, hepatitis granuloma and urethritis.

  • Although abdominal symptoms may mimic those of appendicitis, Enterobius is at least as common in normal as in inflamed appendices.
  • Cases of Enterobius prostatitis and peritonitis have been reported.
  • Adults and ova of Enterobius have been identified in the kidneys and eyes of infested patients.